Question

The multidrug-resistance protein, which can lead to drug resistance in cancer and other pathological situations, is present in most normal cells. what purpose might this protein serve in normal cells?

Answer 1

he MRP proteins are found throughout the nature and they mediate many importantfunctions. .... In tumor cells, the 190 kDa MRP1 can confer resistance to not only doxorubicin, but many other widely used antineoplastic drugs, including methotrexate (MTX), daunorubicin, vincristine and etoposide [5, 23, ...