In the beta- oxidation pathway, the fatty acid diffuses to the mitochondrial membrane where it is combined with carnitine.
The Beta-oxidation pathway is the process by which fatty acids are broken down into smaller fragments with the release of energy with each repetition of beta-oxidation one acetyl CoA is released from the fatty acid carbon chain. Fatty acid oxidation is initiated on the outer mitochondrial membrane. The activation is catalyzed by acyl-CoA synthetase. For each molecule of fatty acid activated, one molecule of coenzyme A and one molecule of adenosine triphosphate (ATP) are used, equaling a net utilization of the two high-energy bonds in one ATP molecule. The fatty acyl-CoA diffuses to the inner mitochondrial membrane, where it combines with a carrier molecule known as carnitine in a reaction catalyzed by carnitine acyltransferase.
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