Nucleotide excision repair comes first. Specific endonuclease enzymes eliminate nucleotides containing damaged bases via this method. DNA.
Translesion synthesis, bypass synthesis, or error-prone repair are terms used to describe this. When DNA repair has failed to take place before replication, for example, this is the last option. The DNA polymerase switches from catalyzing template-directed synthesis to catalyzing the inclusion of random nucleotides during translesion replication.
Base excision repair (BER), nucleotide excision repair (NER), mismatch repair (MMR), homologous recombination (HR), and non-homologous end joining (NHEJ) are at least five primary DNA repair processes that are active at various periods of the cell cycle and enable the cells to repair DNA damage.
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