Take the prime factorization of each factor in the product.
[tex]\dfrac{72 \times 78 \times 85 \times 90 \times98}{68 \times 84 \times 91 \times 108} \\\\ ~~~~~~~~ = \dfrac{(2^3\times3^2)\times(2\times3\times13)\times(5\times17)\times(2\times3^2\times5)\times(2\times7^2)}{(2^2\times17)\times(2^2\times3\times7)\times(7\times13)\times(2^2\times3^3)} \\\\ ~~~~~~~~ = \dfrac{2^6 \times 3^5 \times 5^2 \times 7^2 \times 13 \times 17}{2^6 \times 3^4 \times 7^2 \times 13 \times 17} \\\\ ~~~~~~~~ = 3 \times 5^2 = \boxed{75}[/tex]