Question

Achondroplasia is a common form of dwarfism caused by autosomal dominant mutation in the fibroblast growth factor receptor 3 (Fgfr3) gene. If a person with achondroplasia (Aa) married and had children with a person of normal height, what is the probability that both their first child and second child would have achondroplasia

Answer 1

The probability that both their first child and second child would have achondroplasia is a P=1/4 (one quarter).

What is Achondroplasia?

Generally, Achondroplasia is simply defined as a genetic disorder in which the formation of long bones through cartilage ossification is slowed,

In conclusion. the probability that both the first child and second child of an achondroplasia patient has achondroplasia is 1/4 or a quarter chance.

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