Answer: There was a single nucleotide polymorphism (SNP) in the second codon and an insertion between the first and second codon
Explanation:
SNP: CCG-TTG-CAT --> CCG-TCG-CAT pro-leu-his --> pro-ser-his, change in one amino acid
insertion: CCG-TCG-CAT --> CCG-ATC-GCA-T pro-ser-his --> pro-ile-ala, change of reading frame