The US region which is most often considered a historical center for finance, medicine, education, and commerce is the Northeast.
This includes for example New York which is considered the center of commerce and finances as well as many Universities, such as Harvard.
Indeed, New York is one of the leading financial and cultural centres of the world, with the highest population of any city in the United States. The city has huge global significance and impact in terms of commerce, media, finance, fashion, art, technology, research, entertainment and education.
