Which factor contributed most to Florida becoming a U.S. territory?
1.) The outcome of the Seminole Wars
2.)The weakening of Spain's hold over its colonial possessions
3.) The desire of Southern politicians to expand slavery into new territories
4.)The development of the Gulf of Mexico as an important commercial waterway
The main factor that contributed most to Florida becoming a U.S. territory would be "2.)The weakening of Spain's hold over its colonial possessions," since this territory was given to the United States by Spain.