During replication, a genetic mutation can occur due to;
• The disappearance of the nucleotide base.
• Addition of any nucleotide in a DNA sequence.
• Substitution of nucleotide base pair.
Further Explanation:
Genetic mutation can develop due to change in a particle sequence of the DNA. It can affect a single sequence or can affect a large sequence of DNA. Genetic mutation can be of two types:
• Somatic mutation: These are the mutation that can develop during the life span of an individual. They are not like hereditary. They can develop due to UV-rays.
• Hereditary mutation: These are the mutation that can pass from parents to offspring. They are also referred to as a germline mutation. They pass through the egg or sperm cell.
During the process of replication, genetic mutation mainly develops due to:
• Deletion: In this, disappearance or deletion of a specific nucleotide can occur and develop a mutation in the DNA. This is an example of a point mutation.
• Duplication: In this, duplication of a particular base pair occurs.
• Insertion: In this, the addition of a specific nucleotide base or nitrogenous base can occur.
• Substitution: In this, the normal base pair is substituted by a different base pair.
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Answer Details:
Grade: High School
Subject: Biology
Topic: Genetic Mutation
Keywords: Genetic mutation, base pair, nitrogenous base, DNA, replication, disappearance, base pair, cell. somatic mutation, germline mutation.
