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The difference is that independent clauses can stand on their own, they are complete and don't need an extension in the form of another sentence. Subordinate clauses, however, are incomplete - they are dependent on a larger, independent sentence.
The similarities would be that they are both types of clauses that may have multiple subjects and predicates, I guess.

A dependent clause is a group of words that also contains a subject and a verb, but it is not a complete thought. A dependent clause is a group of words that also contain a subject and a verb but it is not a complete thought
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