Question

1)The p-value corresponding to the chi-square test of independence on alleles is 0.004. If there are a total of 50 SNPs in the data set, the Bonferroni corrected p-value is?
2)What is the goal of association mapping?
6) In a GWAS with 500,000 SNPs tested among cases and controls, one SNP has a chi-square test-statistic p-value of 0.000001. After Bonferroni correction, is this SNP's p-value significant at the 0.05 level?

Answer 1

Association mapping is being able to identify and quantify the loci among genetic sequences. 

Secondly, p-values are probability values that set if the given result is only by the chance or not. 

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