If the gene for hemophilia is present in the Y chromosome of a man, then 100% of the man's sons will be affected by the disease because a man inherits his Y chromosome to the son, and no daughter will be affected as they get the X chromosome.
Hemophilia is a genetic disorder where the blood becomes unable to clot properly. The disease is X-linked recessive and to be affected both the alleles must be mutated in an individual. Here the gene encoding proteins involved in blood clotting are mutated.
Chromosomes are the compact genetic material that consists of DNA and histone proteins. The structure of chromosome consists of two sister chromatids joined together at the centromere.
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