according to the estrogen protection hypothesis, the hormone estrogen, which is present at higher levels in women than in men, protects against symptoms of schizophrenia via its effects on serotonin and dopamine.

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19-12-2022
Biology

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according to the estrogen protection hypothesis, the hormone estrogen, which is present at higher levels in women than in men, protects against symptoms of schizophrenia via its effects on serotonin and dopamine.

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contexto1220 contexto1220 · Answer 1 · 2022-12-22T20:15:55+01:00

True. according to the estrogen protection hypothesis, the hormone estrogen, which is present at higher levels in women than in men, protects against symptoms of schizophrenia via its effects on serotonin and dopamine.

The estrogen hypothesis has received the most attention, and it proposes that estrogen has a protective effect by protecting females from the onset and intensity of the illness.

Estrogens influence key pathophysiological pathways in schizophrenia, such as dopamine levels, mitochondrial function, and the stress response. Estrogen deficiency affects both sexes and is linked to an increase in psychotic symptoms.

Estrogen promotes dopamine synthesis while inhibiting its degradation, reuptake, and recapture. It also increases the activity of dopaminergic receptors.

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