In Kamin's experiment, the additional stimulus is neither novel nor instructive (pp. 77).
It has been claimed that the summation of pain over time plays a significant role in a number of clinical diseases. There is debate about whether the first pain caused by the A8 fibres has temporal summation. The current human experimental study's goal was to find out how much the stimulus's strength, interpulse interval, and placement affected the temporal summation of pain brought on by radiant (laser) and touch heat. The same or nearby areas of the skin received successive stimulation. Rapid temperature increases were elicited by both stimulation methods, which is a crucial factor in the recruitment of particular cutaneous nociceptors (A and C fibres). Nine volunteers' painful reactions to repeated stimuli applied to their hairy skin were evaluated using psychophysical thresholds and evaluations of pain severity.
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