at puberty, the hypothalamus secretes gonadotropin-releasing hormones (gnrh), causing the secretion of gonadotropins by the pituitary gland. these hormones cause the ovaries to produce estrogen and testes to produce testosterone. as the levels of these hormones rise, they shut down the release of gnrh and the gonadotropins. this example illustrates the a combined signals of excitatory and inhibitory connections. b information highway connecting the peripheral nervous system to the brain. c feedback systems connecting the brain and endocrine systems. d reflex pathways running through the spinal cord. e role of agonists and antagonists in the nervous system.

During this process, the hypothalamus secretes gonadotropin-releasing hormone (GnRH), which stimulates the pituitary gland to release gonadotropins (such as luteinizing hormone and follicle-stimulating hormone).

These gonadotropins stimulate the ovaries to produce estrogen and the testes to produce testosterone. Elevated levels of these hormones act as negative feedback, inhibiting the release of GnRH and gonadotropins, closing the feedback loop.

This process points to the role of feedback systems in regulating hormone production and release. Feedback systems are common in both the nervous and endocrine systems and involve the release of signaling molecules (such as GnRH and hormones) that trigger responses that alter the original signal. In this way, the feedback system helps maintain homeostasis or balance within the body.

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