Peripheral chemoreceptors are specialized cells in contact with arterial blood that respond directly to changes in blood ________.A) pHB) PO2C) PCO2D) PCO2 and PO2E) PO2, pH, and PCO2

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Specialized cells called peripheral chemoreceptors in contact with arterial blood react immediately to variations in blood PO2.

Carotid and aortic bodies, which are peripheral chemoreceptors, sense changes in arterial blood oxygen levels and set off reflexes that are crucial for preserving homeostasis in hypoxemia. The carotid (and aortic) bodies, which act as peripheral chemoreceptors, recognise arterial hypoxia and promote breathing. They give the brain stem a constant excitatory input at normal arterial PO2 (PaO2) values (6), and in hypoxia, they react dramatically as PaO2 drops below 70 Torr. With some help from [H+], peripheral chemoreceptors are particularly sensitive to changes in PaO2. The peripheral chemoreceptor hypoxic response predominates in situations where the receptors disagree, such as hypoxic hypocapnia, causing the respiratory drive to increase oxygenation despite additional reductions in CO2.

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