To recap, intracellular receptors are inside the cell, whereas membrane receptors are attached to the cell's plasma membrane.
Intracellular receptors interact with ligands found within the cell, whereas membrane receptors interact with ligands found outside of the cell.
Signaling chemicals and the receptors on target cells to which they attach. Intracellular receptors, ligand-gated ion channels, G protein-coupled receptors, and receptor tyrosine kinases.
GPCRs and single-pass transmembrane proteins are the two most common types of transmembrane receptors. The transmembrane region of certain receptors, such as the nicotinic acetylcholine receptor, generates a protein hole through the membrane or surrounding the ion channel.
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