False, be should if the pure genome of the virus in Paramyxoviridae is inserted into a permissive cell, the formation of multinucleated giant cells (syncytia) will result.
Fusion glycoproteins work together to mediate membrane fusion and entry of particles into susceptible host cells. Following the attachment of the virus to the permissive, receptor-containing host cell, virion and plasma membrane fusion occurs, resulting in the transport of the viral nucleocapsid into the cytoplasm. In a similar process, cells expressing glycoproteins that adhere and fuse to their surface can associate with receptor-bearing cells under physiological or cell culture conditions, resulting in the formation of multinucleated giant cells (syncytia), a hallmark of many Paramyxovirus infections.
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