The mixing of atmospheric air within the dead space of the conducting zone of the lung upon inspiration results in a partial pressure of, oxygen in the alveoli that is lower than atmospheric (C).
What is the relative pressure in the lungs during inspiration?
- During inhalation, the increased volume of alveoli caused by lung expansion reduces intra-alveolar pressure to a value less than atmospheric pressure, approximately -1 cmH2O. In the two seconds required for inspiration, this slight negative pressure is enough to move 500 ml of air into the lungs.
- The volume of air inhaled that does not participate in gas exchange because it either remains in the conducting airways or reaches alveoli that are not perfused or are poorly perfused is referred to as dead space. It means that not all of the air in each breath is available for oxygen and carbon dioxide exchange.
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