A model of the environmental stress and genetics involved in schizophrenia proposes the interaction of stress and genetic factors.
Phencyclidine and ketamine both of which block glutamate receptors are known to cause psychosis, further suggesting that psychosis and possibly schizophrenia cannot be fully explained in terms of dopamine function.
Clomipramine is FDA-approved for the treatment of obsessions and compulsions in OCD. It is a dibenzazepine compound belonging to the TCA family. Inhibits membrane pump mechanisms involved in the uptake of norepinephrine and serotonin in adrenergic and serotonergic neurons. Studies show that a combination of physical genetic psychological and environmental factors can make you more likely to develop this condition.
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