Changes in chromatin structure can result in the repression or
stimulation of gene expression.
Acetylation of histone proteins increase transcription. The reverse reaction, deacetylation, results in suppression. The chromatin remodeling complex is DNA that alters chromatin structure without acetylating histone proteins, allowing transcription.
A promoter accessible to transcription factors. methylation of a DNA sequence represses transcription. Demethylation of DNA
Sequences often increase transcription.
Gene expression in eukaryotic cells is regulated by both repressors and transcriptional activators. Like their prokaryotic counterparts, eukaryotic repressors bind to specific DNA sequences and inhibit transcription.
Gene regulation can occur at any point in the transcription-translation process, but most commonly occurs at the transcriptional level. Proteins that are activated by signals from other cells or the environment are called transcription factors.
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