Because E-codes are the most commonly used and are used by all medical specialties, they are listed first in the CPT. The CPT coding system specifies how procedures and services should be reported. The American Medical Association maintains and protects the CPT system. Each CPT code is made up of five digits.
HCPCS codes are a distinct set of codes used to describe drugs, supplies, and certain other non-CPT services. HCPCS codes, like CPT codes, have 5 characters, but the first is a letter and the remaining characters are numbers. CMS, not the AMA, administers the HCPCS codes.
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