Everyone is exposed regularly to ionizing radiation found in the soil, water, and air and from cosmic rays. In fact, 80% of the ionizing radiation people are exposed to comes from naturally occurring sources. Ionizing radiation can cause double-strand breaks in the DNA. Often, the DNA breaks have missing nucleotides at the broken ends. What type of repair would likely be used, and what would be the result of repairing this type of damage?
A. Nonhomologous end joining would be used and would lead to properly repaired DNA.
B. Direct repair would be used to join the DNA, but errors would still remain.
C. Nonhomologous end joining would be used to join the DNA, but errors would still remain.
D. Direct repair would be used and would lead to properly repaired DNA.
C

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BrennaLu8146 BrennaLu8146

30-11-2022
Biology

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Everyone is exposed regularly to ionizing radiation found in the soil, water, and air and from cosmic rays. In fact, 80% of the ionizing radiation people are exposed to comes from naturally occurring sources. Ionizing radiation can cause double-strand breaks in the DNA. Often, the DNA breaks have missing nucleotides at the broken ends. What type of repair would likely be used, and what would be the result of repairing this type of damage?
A. Nonhomologous end joining would be used and would lead to properly repaired DNA.
B. Direct repair would be used to join the DNA, but errors would still remain.
C. Nonhomologous end joining would be used to join the DNA, but errors would still remain.
D. Direct repair would be used and would lead to properly repaired DNA.
C

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The result of repairing this type of damage would be d. Non-homologous end joining would be used to join the DNA, but errors would still remain.

Non-homologous end joining (NHEJ) without a homologous sequence is used to fix the double-strand breaks.

DNA ligase IV binds the two ends after the double-strand break removes some nucleotides from them. First, Ku proteins bind to the ends and recruit DNA-PKcs, which in turn recruits Artemis, a nuclease, to get rid of any single-stranded DNA in that area.

The DNA would be joined using non-homologous end joining (NHEJ), but there would still be errors because NHEJ only deletes a small number of nucleotides. Therefore, this is a blunder-inclined fix system.

Know more about DNA ligase here: https://brainly.com/question/28334130

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