What is Nucleophilic Acyl Substitution?
A reaction known as nucleophilic acyl substitution occurs when a nucleophile forms a new bond with an acyl group's carbonyl carbon while simultaneously breaking the bond between the carbonyl carbon and a leaving group.
Explanation:
In two phases, (1) addition and (2) elimination, a nucleophilic acyl substitution takes place.
The carbonyl center is added to by a nucleophile during the addition step, forming a tetrahedral intermediate.
The tetrahedral intermediate initially formed in the reaction is given as,
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