For the given statement , correct answer is option e: there is either no association or a negative association between the factor and the disease.
Reason with explanation:
The complete question is:
In a study of a disease in which all cases that developed were ascertained, if the relative risk for the association between a factor and the disease is equal to or less than 1.0, then:
a. There is no association between the factor and the disease
b. The factor protects against development of the disease
c. Either matching or randomization has been unsuccessful
d. The comparison group used was unsuitable, and a valid comparison is not possible
e. There is either no association or a negative association between the factor and the disease
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