Between ALS patients with spinal onset and those with bulbar onset, no appreciable changes in blood AP and glucose levels were found. However, in patients with spinal onset ALS, a statistically significant positive connection was seen between the mean values of both chemicals.
What is bulbar onset ALS?
Lou Gehrig's disease, also known as amyotrophic lateral sclerosis (ALS), is a complex illness that can present itself in a variety of ways; each case is different. The area of the body where ALS first manifests itself can differ from person to person. Bulbar-onset ALS is characterized by the onset of symptoms in the neck or face. This name derives from the "bulbar" area of the brain, which regulates facial and neck muscles as well as functions like swallowing and speech.
Hence the answer is, the muscle function differences depend on peripheral glucose.
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