Digoxin is a safe and effective drug that has a wide therapeutic dosing range and limited risk of toxicity is false.
When treating hypotension or when using beta-blockers is absolutely contraindicated, digoxin may be helpful. The prognosis of individuals with HF and left ventricular systolic dysfunction, a significant portion of whom had as their baseline rhythm, has only been demonstrated to improve with beta-blockers.
Digoxin may help with some symptom alleviation because a fast heartbeat is a major contributor to atrial fibrillation symptoms. However, the atrial fibrillation symptoms are better controlled by beta-blockers and calcium channel blockers, which are now often used to treat atrial fibrillation.
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