Answer:
Diagnostic Procedures: DNA testing: To isolate the mutation
Pulmonary function tests (PFTs): Evaluate the small airways
Chest x-ray: Can indicate diffuse atelectasis and obstructive emphysema Abdominal x-ray: Detect meconium ileus
Stool analysis: For the presence of fat and enzymes
Duodenal analysis: Analyze pancreatic trypsin levels (NG tube)
Sweat chloride test: The child must be well hydrated to ensure accurate test results. A device that uses an electrical current stimulates sweat production. Collection of sweat from two different sites for adequate sample.
Expected reference range is chloride content less than 40 mEq/L and sodium content less than 70 mEq/L (Chloride greater than 40 mEq/L for infants less than 3 months of age and greater than 60 mEq/L for all others; sodium greater than 90 mEq)
