Question

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Which is the correct biochemical sequence in the pathway for synthesis of the amino acid arginine?


a) ornithine is converted to arginine, which is then converted to citrulline


b-) citrulline is converted to arginine, which is then converted to ornithine


c-) arginine is converted to citrulline, which is then converted to ornithine


d-) ornithine is converted to citrulline, which is then converted to arginine

Answer 1

The correct biochemical sequence in the pathway for synthesis of the amino acid arginine is : Ornithine is converted to Citrulline, which is then converted to Arginine.

All living things use the amino acids arginine and ornithine as building blocks for a variety of nitrogenous molecules. The sequential actions of the enzymes ornithine transcarbamylase (OTC), argininosuccinate synthetase (ASSY), and argininosuccinate lyase catalyze the metabolic conversion of ornithine into arginine (ASL).

The OTC-catalyzed process is a regulatory target in the homeostasis of ornithine pools that can be employed for the manufacture of arginine in plastids or other nitrogenous compounds in the cytosol, among other nitrogenous compounds.

Ornithine transcarbamylase (OTC), argininosuccinate synthetase (ASSY), and argininosuccinate lyase function sequentially to convert glutamate into ornithine, ornithine is converted to Citrulline and produce arginine from ornithine, respectively, in the two pathways that make up the biosynthesis of arginine (ASL)

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