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DNA ligase helps in joining the two strands of DNA
DNA ligase is a selected type of enzyme, a ligase that helps the becoming a member of DNA strands together by means of catalysing the formation of a phosphodiester bond.
DNA ligase is a DNA-joining enzyme. If two portions of DNA have matching ends, ligase can link them to form a combined, unbroken molecule of DNA. In DNA cloning, restriction enzymes and DNA ligase are used to insert genes and different pieces of DNA into plasmids.
DNA ligases play an essential function in preserving genomic integrity by becoming a member of breaks inside the phosphodiester backbone of DNA that occur for the duration of replication and recombination, and are attributable to DNA damage and its restore. 3 human genes, LIG1, LIG3 and LIG4 encode ATP-dependent DNA ligases
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