In order for successful antibiotic therapy, the in vivo level of the antibiotic must be greater than or equal to the MIC is a true statement.
Antibiotics are only effective against bacteria that are growing and dividing. The minimum inhibitory concentration (MIC) is the lowest concentration of an antibiotic that will inhibit the growth of a particular bacterium.
In order for an antibiotic to be effective, the concentration of the antibiotic in the body must be greater than or equal to the MIC. If the concentration of the antibiotic is less than the MIC, the bacteria will continue to grow and divide.
If the concentration of the antibiotic is equal to or greater than the MIC, the bacteria will be inhibited from growing and dividing.
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