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During skeletal muscle activation, each myosin requires ____ atp per cross bridge cycle, and myosin heads cycle ____.

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During skeletal muscle activation, each myosin requires two ATP per cross bridge cycle, and myosin heads cycle once.

The neuromuscular junction, which is the synapse between a motoneuron and a muscle fiber, is where skeletal muscle contraction begins. The opening of voltage-gated calcium (Ca2+) channels of the presynaptic membrane occurs as a result of action potential propagation to the motoneuron and subsequent depolarization.

Skeletal muscles are made up of many individual muscle fibers that are stimulated by motor neurons in the spinal cord. They are grouped together to form "motor units," and each motor unit may contain more than one type of muscle fiber.

NMJs are excitatory chemical synapses that form between nerve terminals of spinal cord motor neurons and skeletal muscle fibers and use acetylcholine as a neurotransmitter.

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