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Silent mutation which does not always the result in the abnormal amino acid sequence

A silent mutation occurs when changing a single DNA nucleotide within the protein-coding portion of a gene does not affect the sequence of amino acids that make up the gene's protein. Silent mutations are mutations in DNA that have no observable effect on the phenotype of an organism. They are a specific type of neutral mutation. The term "silent mutation" is often used interchangeably with the term "mutation". However, synonymous mutations are not always silent and vice versa. A silent mutation is a type of substitution or point mutation in which changes in the DNA sequence of a gene do not affect the amino acid sequence. For example, AAA (which encodes the amino acid Lysine, Lys) mutates to AAG (which also encodes Lys).

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