The transitions that occur as a 300A fiber are created as chromosomal condensation takes place. It looks to be made up of five or six tightly wound nucleosomes. A solenoid is a structure of this type.
About two meters of the human genome's DNA must be compressed into chromatin that fits inside a cell nucleus that is a few microns across in order for the information encoded in DNA to stay accessible.
This coiling of the DNA double helix repeatedly around the histones creates nucleosome arrays, which are then folded into higher-order structures. The nucleosomes are separated by relatively straight DNA linkers, and the distance between adjacent nucleosomes varies between different cells and chromosomal locations.
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