No, a 300 cc blood loss would not be fatal as the majority of humans have 4-6 liters of blood.
Blood type Rh
RhD positive people make up about 85% of the population, whereas RhD negative people make up the remaining 15%. Because the D antigen is highly immunogenic, people who are RhD negative but receive blood that is RhD positive are likely to develop anti-D antibodies.
Globulin - transport and immunity is the right response (a). In addition to ions and lipids, globulin proteins have the ability to transport a wide range of molecules throughout the plasma. The immune system can also benefit from a subclass of globulin proteins known as gamma globulins.
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