The general equation of a circle is:
[tex](x-h)^2+(y-k)^2=r^2[/tex]where (h, k) is the center and r is the radius.
From the graph, the center is located at (4, -2), that is, h = 4, and k = -2. And the radius is 4, that is, r = 4. Substituting into the general equation, we get:
[tex]\begin{gathered} (x-4)^2+(y-(-2))^2=4^2 \\ (x-4)^2+(y+2)^2=16 \end{gathered}[/tex]Solving the square of the binomials, and combining similar terms:
[tex]\begin{gathered} \lbrack x^2+2\cdot x\cdot(-4)+(-4)^2\rbrack+\lbrack y^2+2\cdot y\cdot2+2^2\rbrack=16 \\ x^2-8x+16+y^2+4y+4-16=0 \\ x^2+y^2-8x+4y+(16+4-16)=0 \\ x^2+y^2-8x+4y+4=0 \end{gathered}[/tex]