Answer: Option 'C' is correct.
Step-by-step explanation:
The investigational new drug (IND) application contains
Safety and effectiveness of the test drug after FDA approval
As Investigation would contain how much it is effective and how much the test is safe for the animals.
Toxicity of the test drug in animals is done before the FDA approval .so, the investigational new drug would not contain this.
Hence, Option 'C' is correct.