Question

in a given bacterium, transcription of housekeeping genes is normal, but genes involved in nitrogen metabolism, stress, and chemotaxis are disrupted. which sigma subunit is intact?

Answer 1

σ70 subunit is intact hence, chemotaxis are disrupted

What is Sigma subunit ?

All bacterial RNA polymerases contain sigma factors as subunits. They decide the specificity of promoter DNA binding and manage the effectiveness of RNA synthesis (transcription) initiation. Sigma70 (70) of the well researched bacteria Escherichia coli was the first sigma factor to be identified.

• The initial and most tightly controlled phase of gene expression is transcription. All genes in bacteria are transcribed by sigma () factors, which are universal transcription factors that reversibly bind RNA polymerase (RNAP).

• When RNA polymerase binds to promoter sites in DNA sequences, transcription can begin. This is facilitated by sigma factor proteins. The cellular environment has an impact on sigma factors, which are gene-specific. Both transcription and translation can be regulated by sigma factors.

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