Fischer esterification reaction requires an acid to synthesize an ester from a carboxylic acid and an alcohol to form an ester.
C4H8OH + C2H40 → C6H13COO
Reaction mechanism:
CH3COOH + H2SO4 → C2H(OH)2 + SO3OH → C5H9(OH)3 + SO3(OH)
→C6H13COO + H20 + H2SO4
Since the entire process is reversible, the Fischer Esterification Mechanism also requires a significant excess of alcohol or the constant removal of water from the system. Fischer An ester is the end result of the organic reaction known as esterification, which is used to change carboxylic acids in the presence of abundant alcohol and a powerful acid catalyst. Water is a component of the ester formation. The methods for removing water from the system during this esterification include azeotropic distillation and molecular sieve adsorption. A nucleophilic acyl substitution reaction, such as this one, is exemplified by the reaction. The alcohol's nucleophilicity and the carbonyl carbon's electrophilicity form the basis for the substitution.
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