To compensate for clopidogrel’s slow onset of action, the nurse should anticipate implementing intervention of one-time loading dose administration higher than the maintenance dose.
By making platelets less sticky, clopidogrel reduces the rate at which blood clots. Blood cells called platelets clump together to seal rifts and tears in blood vessels. However, platelets can congregate and form a clot in already constricted blood channels if you are at risk of having a heart attack or stroke. When adenosine diphosphate (ADP) binds to the platelet P2Y12 receptor and then activates the glycoprotein GPIIb/IIIa complex, the active metabolite of clopidogrel specifically prevents platelet aggregation.
The drug clopidogrel belongs to the group of drugs known as antiplatelet drugs. It functions by preventing platelets, which are a particular type of blood cell, from accumulating and creating clots that might lead to a heart attack or stroke.
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