There is a huge diversity in Bacterial organisms. We are very ignorant of the bacterial life present on earth. But many of these bacteria are unculturable in the Natural Environment which might not be suitable for their survival or the competition between other microbes. It is also estimated that less than 2% of bacteria can be cultured in Laboratory.
The bacterias can be unculturable due to several reasons. Some of them are: The culture may not allow bacteria to get the essential nutrients, the Medium can be toxic, or other bacteria produce substances that make it inhabitable for the target organism. We know that bacterias depend on each other for their growth and complete nutritional requirement which can make it unculturable for other bacteria to grow.
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