The active genes are less methylated than the inactive genes in a DNA.
The active genes are those are involved in the process of gene expression. These genes can perform replication, transcription and then translation to express the genetic information in the form of proteins.
DNA methylation is the process of adding methyl group to the cytosine residue of the DNA. This is an epigenetic change that inhibits the DNA from gene expression. The methylation process can repress gene activity in two ways: It can recruit proteins involved in gene repression or it can inhibit the binding of the transcription factors to DNA.
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