Naturally occurring endonucleases are very effective against: Bacteriophages
- DNA is cut at specific places along the molecule by a bacterial protein known as a restriction enzyme, often referred to as an endonuclease.
- In the bacterial cell, restrictions enzymes cut foreign DNA, destroying the infected organisms.
- A bacterium defends itself against bacteriophages, also known as phages, which are bacterial viruses by using a restriction enzyme.
- When a phage infects a bacterium, it inserts its DNA into the bacterial cell so that it can reproduce.
- The restriction enzyme prevents the phage DNA from replicating by cutting it into several pieces.
- Restriction enzymes earn their name because they can restrict the range of bacteriophage strains that can infect a bacteria.
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