HPA axis means hypothalamic–pituitary–adrenal (HPA) axis, which is the major component of stress response because whenever a person has stress, then stress hormones known as glucocorticoids are released.
Stress can now induce nerve cells in one region of the brain, which is called the hypothalamus, to produce and release the corticotropin-releasing factor (CRF).
CRF is the main central regulator of the HPA axis, and this CRF stimulates the release of a hormone that produces morphine-like effects through the autonomic nervous system and human brain start send the electrical impulses and the body starts responding to the stress.
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