The process whereby the flow of filtrate through the distal tubule results in changes in GRF is termed tubuloglomerular feedback.
- An adaptive mechanism called tubuloglomerular feedback connects the level of salt in the tubule fluid at the macula dense to the rate of glomerular filtration. Contraction of the afferent arteriole and a decrease in GFR are brought on by a high [NaCl] and reabsorption rate at this location.
- A test called the glomerular filtration rate measures how efficiently the kidneys are functioning. In particular, it calculates the volume of blood that flows through the glomeruli each minute. The normal range is still regarded as including a GFR of 60 or higher. If your GFR is below 60, you may have kidney disease. A GFR of 15 or lower may indicate renal failure.
To learn more about glomerular filtration.
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