The correct answer is option D
In cells treated with toxic rotenone, the concentration of NADH will increase.
Rotenone is the active chemical substance that inhibits the complex 1 electron transport chain activity of the mitochondria.
Mitochondria is the power of the house that helps in the production of ATP. Nicotinamide Adenine Dinucleotide hydrogen (NADH) produced from the citric acid cycle is given to the mitochondrial complexes.
In complex 1 of the mitochondria, NADH is converted into NAD and the hydrogen is liberated. The liberated hydrogen helps in the creation of the proton motive force. With the proton motive force, Complex 5 generates the energy currency of the cell Adenosine triphosphate (ATP).
As this conversion of NADH to NAD is inhibited by rotenone the amount of NADH in the cell will increase.
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What will happen if the cell is treated with the toxin rotenone that inhibits the electron transport chain?
A) concentration of pyruvate will decrease
B)Concentration of ATP will increase
C) Concentration of oxygen will increase
D) Concentration of NADH will increase
