Respuesta :
A young child with marked respiratory distress who is agitated and thrashing about should receive oxygen via a method that minimizes metabolic demand and oxygen consumption.
The utilization of energy by the working heart has been studied extensively over the years. Because the conversion of chemical energy to mechanical work by the heart is highly dependent on oxygen, the oxygen required and the oxygen available for this conversion are considered to form the conceptual framework of the metabolic demand and supply of the heart, respectively. The oxygen requirement of the myocardium, as assessed by the rate of oxygen consumed (MVO2), is a function of the mechanical components of ventricular contraction and include: (1) the force developed and sustained by the muscular wall during its contraction; (2) the rate of force development; and (3) the frequency of generating force in the wall per unit time. The oxygen available to the mitochondria, which satisfies this requirement, is primarily determined by the oxygen delivered per unit of time (that is, coronary flow) and the oxygen extracted. Collectively, the response in flow and oxygen extraction represent the metabolic reserve of the heart.
How much does blood flow to the brain meet metabolic demand?
The promising reality here is that for any given amount of weight support, metabolic demand can be increased by increasing walking or running speed. Normally CBF is coupled to metabolic demand of tissue, with normal flow greater than 50 ml/100 g/min.
Learn more about metabolic demand here
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