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The bone cell responsible for breaking down bone tissue is the osteoclast, whereas the bone cell that produces new bone tissue is the osteoblast.

What is osteoclast and osteoblast?

  • In those processes, osteoblast and osteoclast are the two major cells involved.
  • Aged bone resorption is caused by osteoclasts, whereas new bone creation is caused by osteoblasts.
  • Under healthy settings, the processes of resorption and creation are steady.
  • The cells known as osteoclasts mediate bone loss in pathologic situations by increasing their resorptive activity and degrading bone to start normal bone rebuilding.
  • They originate from myeloid/monocyte lineage progenitors that circulate in the circulation after developing in the bone marrow.
  • On the surface of bones, there are osteoblasts, bone lining cells, and osteoclasts, which develop from progenitor cells, which are regional mesenchymal cells.
  • Osteocytes are created by the fusing of mononuclear blood-borne progenitor cells, and they penetrate the interior of the bone.

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