The release of histamine during a type I hypersensitivity reaction contributes to swelling.
Histamine is an organic nitrogenous compound involved in local immune responses. It is found in the mast cells of the body and acts like a bouncer in helping you get rid of something that is bothering your body i.e. allergen.
When histamines leave the mast cells, blood flow increases in the area affected by the allergen. This causes inflammation or swelling.
This allows other chemicals from your immune system to step in to do repair work.
Hypersensitivity reactions are immunologic responses that occur against an antigen or allergen.
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