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Ionotropic receptors are associated with ligand-activated ion channels, whereas metabotropic receptors are associated with signal proteins and g proteins.

What is the difference between metabotropic and ionotropic receptors?

Ionotropic and metabotropic receptors are two types of receptors that function in membrane transport and signal transduction.

Ionotropic receptors bind to ionic ligands such as K+, Na+, Cl–, and Ca2+.

Metabotropic receptors bind with non-ionic ligands such as chemical receptors or G protein-coupled receptors.

What are metabotropic receptors associated with?

Metabotropic receptors act either directly or indirectly as signal transduction enzymes, or are linked to enzymes that have an extracellular domain recognizing a drug and an intracellular domain that catalyzes a biochemical response.

Learn more about receptors here:

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